The Tumor Microenvironment: A Malignancy Bunker

The Tumor Microenvironment: A Malignancy Bunker

The tumor microenvironment (TME) or tumor niche is a highly heterogeneous complex that is comprised of cells such as stromal cells, immune cells, epithelial cells, and a network of extracellular macromolecules. This complex provides support for cancer cells within the extracellular matrix (EC) and plays a key role in promoting their progression into a more…