Microbiome-Brain

The Gut Flora and Alzheimer’s Disease (AD)

The hallmark of Alzheimer’s disease (AD) is associated with the accumulation of “senile” plaques that are composed of amyloid-beta (Aβ) protein that surround neurons in affected regions. This accumulation results in loss of neurons in the hippocampus and cerebral cortex, leading to progressive cognitive decline such as memory defects. A connection between the brain and…

Cancer Stem Cells

Cancer Stem Cells and Resistance to Drugs

Stem cells are responsible for the generation of all tissues and organs within the body. When these cells become mutated at the gene level (DNA), they become cancerous and are named cancer stem cells [1]. These cancer cells are thought to provide resistance to chemotherapy and relapse in cancer patients. The mutations can affect embryonic…

Chronic Inflammation and Longevity

Chronic inflammation and longevity

Several studies have identified a link between chronic inflammation and longevity [1]. Although inflammation, such as acute inflammation is an essential event in immune response and tissue homeostasis, chronic inflammation has been associated with chronic diseases, including diabetes, cardiovascular diseases, neurodegenerative diseases, and cancer. These diseases are the main causes of bad quality of life,…